The Siamese flat-barbelled catfish was first identified by Dr. Harmand in 1883 from a specimen he collected in the Chao Phraya River. In 1923, Dr. Hugh M. Smith collected a specimen from the Pak Nam Pho Market. He said the species was abundant in the Chao Phraya River including a region of that river called the Nakhon Nayok River. Smith’s specimen was sent to the Smithsonian in Washington DC. The only other specimen of the Siamese flat-barbelled catfish can be found at the Fisheries Natural History Museum at Kasetsart University. There are several factors that led to the extinction of this unique catfish and the endangerment of many other fish species. The urbanization of Thailand and increase of pollution of the Chao Phraya River is thought to be a major cause of extinction. The addition of dams, canals, and drainage of wetlands also impacted this species. Although Jurassic Park is fiction, scientists are working on several de-extinction projects. In fact, in 2003 scientists did bring back the extinct Pyrenean ibex, a type of wild goat, for 7 minutes before it died, showing de-extinction is possible. The Siamese flat-barbelled catfish might be a candidate. Scientists would potentially use DNA from the two specimens of the Siamese flat-barbelled catfish. This soft tissue could be used to bring back this catfish. Thailand has 2,940 species of fish. There are 72 species that are listed as endangered and 53 critically endangered species. The Siamese flat-barbelled catfish is the only extinct species in Thailand. While some efforts are being made to protect and preserve Thailand’s unique wildlife, there are many species still in danger of becoming extinct. In recent years, the long hammerhead shark, narrow beaked snakehead, largetooth sawfish, and narrow snout sawfish have gone extinct from Thailand waters. Would the Siamese flat-barbelled catfish be able to survive if it was returned to the Chao Phraya River in Thailand?